In the June issue there is a special section on Clostridium difficile. Among the articles in this section there are papers from the US, Canada and Spain reporting on the costs and impact of CDI in hospitals. In an interesting paper by Halstead et al it was found using WGS that toxigenic strains from asymptomatic carriers in intermediate care facilities were genetically similar to those causing symptomatic infections. The authors concluded that asymptomatic carriers may be important for the transmission of symptomatic CDI. Another paper addressing the question of why people get CDI, is by McLure et al, who suggest that seasonal variation in antibiotic prescribing is the main driver of seasonal CDI. Amongst the general papers there are three interesting review articles that are well worth reading. These address FMT for decolonisation of gastrointestinal carriage of AMR bacteria, the contribution of WGS to understanding the epidemiology and control of MRSA, and behavioural interventions to reduce UTI and E. coli BSI in older adults. Amongst other papers in the issue, a report of activity of octenidine dihydrochloride and ultraviolet-C light against Candida auris is timely, given recent press interest in this pathogen in the UK.